Searchable abstracts of presentations at key conferences in endocrinology

ea0013p150 | Diabetes, metabolism and cardiovascular | SFEBES2007

Bcl-2 upregulation mediates the protective effect of fluvastatin against oxidative damages in human vascular endothelial cells

Xu Shang-Zhong , Zhong Wenwen , Lindow Steve , Newton Christopher , Atkin Stephen L

Many evidences have shown that the beneficial effect of statins on the cardiovascular disease may be not only due to their cholesterol-lowering, but also may result from their non-lipid related effects, such as the improvement of endothelial function, the inhibition of smooth muscle proliferation, etc\. Here we investigated the effect of fluvastatin on H2O2-induced oxidative cell damage and the underlying mechanism in human umbilical vein endothelial cell...